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Page 1
Prostate lineage-specific metabolism governs luminal differentiation and response to antiandrogen treatment.
Giafaglione JM, Crowell PD, Delcourt AML, Hashimoto T, Ha SM, Atmakuri A, Nunley NM, Dang RMA, Tian M, Diaz JA, Tika E, Payne MC, Burkhart DL, Li D, Navone NM, Corey E, Nelson PS, Lin NYC, Blanpain C, Ellis L, Boutros PC, Goldstein AS. Giafaglione JM, et al. Among authors: crowell pd. Nat Cell Biol. 2023 Dec;25(12):1821-1832. doi: 10.1038/s41556-023-01274-x. Epub 2023 Dec 4. Nat Cell Biol. 2023. PMID: 38049604 Free PMC article.
MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer.
Crowell PD, Giafaglione JM, Jones AE, Nunley NM, Hashimoto T, Delcourt AML, Petcherski A, Agrawal R, Bernard MJ, Diaz JA, Heering KY, Huang RR, Low JY, Matulionis N, Navone NM, Ye H, Zoubeidi A, Christofk HR, Rettig MB, Reiter RE, Haffner MC, Boutros PC, Shirihai OS, Divakaruni AS, Goldstein AS. Crowell PD, et al. Cell Rep. 2023 Oct 31;42(10):113221. doi: 10.1016/j.celrep.2023.113221. Epub 2023 Oct 9. Cell Rep. 2023. PMID: 37815914 Free article.
Aging of the progenitor cells that initiate prostate cancer.
Freeland J, Crowell PD, Giafaglione JM, Boutros PC, Goldstein AS. Freeland J, et al. Among authors: crowell pd. Cancer Lett. 2021 Sep 1;515:28-35. doi: 10.1016/j.canlet.2021.05.014. Epub 2021 May 28. Cancer Lett. 2021. PMID: 34052326 Free PMC article. Review.
Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate.
Crowell PD, Fox JJ, Hashimoto T, Diaz JA, Navarro HI, Henry GH, Feldmar BA, Lowe MG, Garcia AJ, Wu YE, Sajed DP, Strand DW, Goldstein AS. Crowell PD, et al. Cell Rep. 2019 Aug 6;28(6):1499-1510.e6. doi: 10.1016/j.celrep.2019.07.007. Cell Rep. 2019. PMID: 31390564 Free PMC article.
CD38 is methylated in prostate cancer and regulates extracellular NAD.
Mottahedeh J, Haffner MC, Grogan TR, Hashimoto T, Crowell PD, Beltran H, Sboner A, Bareja R, Esopi D, Isaacs WB, Yegnasubramanian S, Rettig MB, Elashoff DA, Platz EA, De Marzo AM, Teitell MA, Goldstein AS. Mottahedeh J, et al. Among authors: crowell pd. Cancer Metab. 2018 Sep 21;6:13. doi: 10.1186/s40170-018-0186-3. eCollection 2018. Cancer Metab. 2018. PMID: 30258629 Free PMC article.